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| Product Name: |
Pam3CSK4
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| Supply Ability: |
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| Related proudcts |
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| Specifications |
Pam3CSK4 |
| Price Term: |
FOB |
| Port of loading: |
Chengdu |
| Minimum Order |
100mg |
| Unit Price: |
1-1000USD |
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Name: Pam3CSK4
Specificity: TLR 1/2 agonist
Working concentration: 1 - 300 ng/ml
CAS number: 112208-00-1
Molecular formula: C81H156N10O13S
Molecular weight: 1509.6
Endotoxin level: Solubility: 1 mg/ml in water
Bacterial lipoproteins are a family of proinflammatory cell wall components found in both Gram positive and Gram negative bacteria. The stimulatory activity of bacterial lipoproteins resides in their acylated amino terminus. Pam3CSK4 is a synthetic tripalmitoylated lipopeptide that mimicks the acylated amino terminus of bacterial lipoproteins. Pam3CysSerLys4 (Pam3CSK4) is a potent activator of the proinflammatory transcription factor NF-κB [1]. Recognition of Pam3CSK4 is mediated by TLR2 which cooperates with TLR1 through their cytoplasmic domain to induce the signaling cascade leading to the activation of NF-κB [2].
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| Company: |
Chengdu Youngshe Chemical Co.,ltd
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| Contact: |
Ms. Cecilia Jiang |
| Address: |
Jitai RD |
| Postcode: |
610000 |
| Tel: |
+86-18108235634 |
| Fax: |
86-028-62328193 |
| E-mail: |
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